太太(60岁)在一个月前诊断出乳腺癌 invasive mammary carcinoma ,半个月前做的根除手术.肿瘤大小为15MM X 15MM X 11 MM, ER Positive at 100%, PR Negative at 0%, HER2- Negative for overexpression at 1+, , 腋下淋巴切除了三个,未发现转移. 12/5在一个医院Biopsy 的pathology report说是 7-8 of 9, GRADE 3, 动手术的医院手术Surgical Pathology final report 说是grade 2 。Modified Bloom Richardson score: 6-7/9.
Nuclear score is 2-3/3
Tubular score is 3/3
Mitotic score is 1/3
AJCC Pahologic Tumor Stage: pT1c PNO(sn)pMX
手术前做了MRI 和X ray 胸透视。医生说未发现转移。是STAGE I, GRADE 2 or GRADE 3? 需作Hormonal Therapy.
请问:
1)现在需要做周身骨扫描和周身CT.吗?医生说考虑到副作用,不需要做周身骨扫描和周身CT。
2)医生解释了adjuvant on line Decision making tools for Breast Cancer. 说了做化疗和不做化疗的利弊。听起来似乎做不做区别不大。让我们做决定。请问做不做化疗哪?
Thanks! We will do chemo. My wife's doctor asks her to decide whether to do Chemo or not. What she is worry about is that she got 原发性血小板减少症 when she was youn. She is alright now.We already told her doctor about that.
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This score is in the area where the benefit of chemotherapy is uncertain. There is a clinical trial open right now for this group of patients. I am not sure whether your wife is seen in an institution where the trial is open. Otherwise, I would favor chemo because of high grade and recurrence score of 26 which is more toward 33 (chemo recommended) than 17 (chemo not recommended) although benefit is uncertain and is small if there is any. Take care.