At one’s wit’s end
无计可施 (PW)
anxious, frantic
I need to speak with him to finish the report by tomorrow but he’s not available. I am at my wit’s end.
(MWusingEnglish)at a loss for a means of solving a problem
(thePhraseFinder)
Meaning
Perplexed; unable to think what to do.
Origin
From the Bible, Psalms 107:27 (King James Version):
They reel to and fro, and stagger like a drunken man, and are at their wits' end.
(MWusingEnglish)
