校友HW对此发出质疑：哥们说说哪个科学方式打的比较好？老肖整了10多年的反射弧，病例数足够你老兄用统计分析了，方舟子打假不科学，咱用科学的方法给回击就可以吧？最简单的方式就是公开病例追踪报告。可是除了那次老裘拍板的鉴定会，几年过去了，还有新的报告没有？要说可疑，肖同学拿10万买杀手用铁锤解决问题，那他的反射弧就更可疑了。shame on him。 另外另有学长拿他的手段和上次的王同学的情况比较很不妥。王同学就算有错，也是走投无路所压。肖同学是贪心不足也。
我们都有幸认识肖传国大夫多年。他是一位受国际学术界尊敬的外科医生和科学家，在恢复（脊椎损伤病人的）排尿和排便功能的神经再生研究中，他取得了重大进展。肖传国医生在美国完成了开创性的动物实验研究，阐明支配大腿的运动神经可以用来绕接支配膀胱和排便。这个绕接可以形成一个反射作用（反射弧）来启动来膀胱功能。他研究的成果已经多次发表在同行评议的国际科学期刊上。其他的科学家也已经重复并证实了肖医生的这些研究结果。 肖医生最终鼓起勇气将动物实验研究的成果转化到临床试验上，在中国的脊柱损伤和脊柱裂病人身上开展神经绕接（神经通路重建，即反射弧）手术。在中国，由于缺乏抗痉挛药物antimuscarinics和间歇性导尿术（自插导尿管），神经性膀胱功能障碍成为一种威胁生命的疾病。能缓解神经性膀胱功能障碍的并发症的疗法，就是一种能够拯救生命的成功。神经性膀胱和排大便功能障碍患者的病情是很痛苦的，包括遭受尿潴留、尿失禁、反复感染、肾功能不全、大便失禁、便秘等，生活质量极差。神经通路重建手术是一个非常复杂的手术，需要神经的再生。不应当把手术的成功定义为完全恢复排便排尿功能。这项手术的重点在于收益超过风险。 肖医生的临床研究成果发表在多种学术刊物上，并两次获得Jack Lapides佳作奖，这是奖励在神经泌尿科学界作出重要贡献的科学家的最崇高的国际性大奖之一。2008年，因为他的科学成就，肖医生还获得了国际儿童排尿节制学会颁发的Kelm Hjalmas演讲者（受邀做大会主题发言）荣誉。我们当中的许多人都曾经到中国去检视肖医生治疗过的患者的情况，观摩或者学习他发明的神经通路重建手术。肖医生是一位非常有经验的外科医生，他对患者热情照顾，不知疲倦地培训来自世界各地的医生们，来推广他的神经通路重建手术。 在美国，已经开展过一项独立而且严格的先期试验来检验这项手术的安全性和效益。术后一年的治疗结果最近发表在《泌尿科学杂志》（Journal of Urology）上。在12个月的随访期间，在9位脊髓裂患者中，有7位患者，观察到皮下至膀胱的神经反射弧的构建成立，证明神经通路重建手术的确起了作用。这个成绩是了不起的，肖医生应该得到嘉奖。并且，一部分患者已经展现出大小便排便功能的改善，并将随时间推移而变得更好。术后36个月的成果正在分析中，不久就会发表。该先期试验的数据是支持“肖氏手术”的，现在受NIH（美国国立卫生研究院）资助的临床试验正在开展，以进一步在脊髓裂患者中研究腰椎至骶神经通路重建。还有，在肖医生的帮助和指导下，类似的临床试验也在世界范围内开展。 中国人民和政府应该为肖医生对病人所作出的贡献、对他的科学成就，和他在世界上培训医生以推广这项手术的诚意而自豪。国际科学界对肖医生被拘捕的消息感到震惊。我们这些了解肖医生的人，都对他涉入此案感到难以置信。 肖医生是一个极富同情心的绅士，他的诚实和对本学科作出的开创性的科学成就广受世界同行的尊敬。我们恳请中国政府和有关权威机构公正对待肖大夫，并在案情调查期间保障他的基本人权。在此事件中，请重视肖大夫对世界所作出的科学和人道主义事业的贡献。
谨致
附：英文原件
September 29, 2010
To all:
We have all had the pleasure of knowing Dr. Chuan-Guo Xiao for many years. He is an internationally respected surgeon-scientist who has made major advances in the development of neuroregeneration to restore voiding and bowel function. Dr. Xiao performed groundbreaking animal research in the United States, demonstrating that a motor nerve that innervates the leg can be used to reinnervate the bladder and bowel. This reinnervation allows for development of a reflex to initiate bladder function. The results of his studies were published in peer-reviewed journals and other scientists have replicated Xiao’s findings confirming these results. Dr. Xiao eventually took the courageous step of moving from animal research to human studies and began performing the rerouting procedure on patients with spinal cord injury and spina bifida in China. Neurogenic bladder is life threatening in China due to a lack of both antimuscarinics and intermittent catheterization, and lessening the complications of neurogenic bladder would be considered a lifesaving success. Patients with neurogenic bladder and bowel suffer greatly and endure a host of issues such as urinary retention, incontinence, recurrent infections, renal insufficiency, fecal incontinence, constipation, and poor quality of life. For a procedure as complicated as nerve rerouting requiring nerve regeneration, one cannot expect normalization of bladder and bowel function to be the definition of success. What is important is that the benefits outweigh the risks of the procedure. Dr. Xiao published his clinical results in peer-reviewed journals and was twice honored by the Jack Lapides Essay Contest, one of the most respected international awards given to scientists who make major contributions to the field of neurourology. In 2008, he was named the Kelm Hjalmas Memorial Lecturer from the International Children’s Continence Society for his scientific achievements. Many of us have traveled to China to examine patients treated by Dr. Xiao and/or have been trained by him in the nerve rerouting surgery he invented. Dr. Xiao is a very skilled surgeon who is passionate about patient care and works tirelessly to train physicians around the world in performing his nerve rerouting procedure. In the United States, an independent and very rigorous pilot research trial was performed to test the safety and efficacy of this procedure. The one-year results were recently published in the Journal of Urology. At the 12-month follow-up visit, a cutaneous to bladder reflex was found in 7 of 9 spina bifida patients, confirming that rerouting does occur. This finding by itself is remarkable and Dr. Xiao should be commended. In addition, a number of patients demonstrated improvement in bladder and bowel function, which has continued to improve with longer patient follow-up. The 36-month results are currently being analyzed and will be reported in the near future. The pilot data was supportive of Dr. Xiao’s procedure, and now an NIH sponsored clinical trial is being conducted to further study lumbar to sacral nerve rerouting in spina bifida patients. In addition, similar procedures have been done worldwide, with Dr. Xiao helping to mentor the surgeons at each site. The Chinese people and government should be proud of Dr. Xiao for his dedication to his patients, his scientific achievements, and his willingness to train doctors around the world how to perform his surgery. The International scientific community was shocked to hear of Dr. Xiao’s arrest. Those of us who know Dr. Xiao well find it difficult to believe that he is involved in these attacks. Dr. Xiao is a compassionate man who is respected worldwide for his integrity and his innovative scientific contributions to society. We implore the Chinese government and authorities to treat Dr. Xiao fairly and to protect his human rights as these charges are investigated. Please strongly consider Dr. Xiao’s scientific and humanitarian contributions to the world as facts are gathered in this case.
Sincerely,
Kenneth M. Peters, MD, Professor and Chairman of Urology, Beaumont Hospital, Royal Oak, Michigan（美国Beaumont医院泌尿科主任）
Jack S. Elder, M.D., Chief of Urology, Henry Ford Health System, Associate Director, Vattikuti Urology Institute, Department of Urology, Children's Hospital of Michigan, Clinical Professor of Urology, Case School of Medicine(美国密西根儿童医院泌尿科主任)
Edwin A. Smith M.D., Assistant Clinical Professor of Urology, Emory University School of Medicine, Atlanta, Georgia（美国艾默里大学医学院临床助理教授）
Kevin M. Feber, MD, FAAP, Board Certified in Pediatric Urology, Comprehensive Urology, William Beaumont Children's Hospital,（美国William Beaumont儿童医院医生）
Ananias C. Diokno, M.D., F.A.C.S.Executive Vice President & CMOBeaumont HospitalRoyal Oak, Michigan 48073 USA（美国Beaumont医院执行副总裁）
Juan José de Benito, Urologist, Hospital Nacional de Clínicas, Córdoba, Argentina.（阿根廷国立医院）
William E. Nantau B.Sc., CNIMClinical ManagerClinical Neurophysiology DepartmentBeaumont Hospital Royal Oak（美国Beaumont医院临床神经生理科临床主管）
Evan J Kass MD,FACS,FAAPChief, Division of Pediatric UrologyBeaumont Childrens HospitalProfessor of Urology, Oakland University-William Beaumont School of Medicine（美国Beaumont儿童医院泌尿科主任，奥克兰大学医学院教授）
Jacques Corcos MD.Professor of Urology, McGill UniversityGeneral Secretary of the International Continence SocietyJewish General hospital3755 Cote Ste-CatherineMontreal, Quebec, Canada H3T 1E2（加拿大麦基尔大学泌尿学教授，国际儿童排尿节制学会秘书长）
Jose Gonzalez, M.D., Department of Urology, Beaumont Hospital, Royal Oak, Michigan（美国Beaumont医院泌尿科医生）
Christopher Payne, MD, Associate Professor of Urology, Stanford University Medical School, Stanford, CA 94305-5118（美国斯坦福大学医学院泌尿学副教授）
Kenneth I. Glassberg, MD, Director, Division of Pediatric Urology, Morgan Stanley Children's Hospital of New York-Presbyterian, Professor of Urology, Columbia University, College of Physicians and Surgeons, 3959 Broadway, CHN 1118（美国哥伦比亚大学医学院泌尿学教授，儿童泌尿学分科主任）
Earl Y. Cheng, MD, Associate Professor of Urology, Children’s Memorial Hospital, Chicago, Illinois（美国芝加哥儿童医院泌尿学副教授）
Darius J. Bagli, MDCM, Professor of Surgery, Senior Associate Scientist, Director of Urology Research, Divisions of Urology and Developmental & Stem Cell Biology, The Hospital For Sick Children, Institute of Medical Science, University of Toronto（加拿大多伦多大学外科学教授，泌尿学研究主任）
Henri B. LOTTMANN, MD, FEBU, FEBPS, FRCS(england) FEBPU, Paediatric urology unit, Hopital Necker-Enfants-Malades, 149, rue de Sèvres, 75015 Paris, France（法国Necker-Enfants-Malades医院儿童泌尿科医生）
Dr. Amrish Vaidya MS. MCh.Consultant Paediatric Surgeon,Kokilaben Dhirubhai Ambani Hospital,4 Bungalows, Andheri W, Mumbai, India, （印度Kokilaben Dhirubhai Ambani医院医生）
Marc Cendron, MD, Associate Professor in Urology, Harvard Medical School, Children’s Hospital Boston, Boston, MA（美国哈佛大学医学院泌尿学副教授）
Stuart B. Bauer, MD, Associate Director, Neurourology, Professor of Urology, Harvard Medical School, Children’s Hospital Boston, Boston, MA（美国哈佛大学医学院泌尿学教授，波士顿儿童医院神经泌尿科副主任）
Edmond T. Gonzales, Jr., MD, Professor of Urology, Baylor College of Medicine, （美国贝勒医学院泌尿学教授）
Richard Macchia, MD FACS, SUNY Distinguished Teaching Professor, Cleveland Clinic, Florida（美国Cleveland临床中心教授）
Benjamin Girdler, MD, Urology Center of the Rockies, Fort Collins, Colorado, （美国科罗拉多洛基泌尿中心医生）
William C. de Groat, Ph.D., Professor of Pharmacology, University of Pittsburgh, （美国匹兹堡大学药理学教授）
Michael R. Ruggieri, Sr., Ph.D., Director of Urologic Research, Temple University School of Medicine（美国坦普大学医学院泌尿学研究主任）
Stanley J Kogan MDChief, Pediatric UrologyChildren's Hospital at MontefioreBronx NY USA（美国Montefiore儿童医院儿童泌尿科主任）
Anthony Caldamone, MD, University Urologic Associates, Inc.2 Dudley St Ste 185Providence, RI 02905（美国布朗大学泌尿学中心医生）
Yves Homsy MD, FRCSC, FAAP Clinical Professor of Urological Surgery and Pediatrics University of South Florida Children's Urology Group 5507 E. Longboat Blvd Tampa FL 33615（美国南弗罗里达大学临床泌尿学教授）
Dr. Enrique Turina, Professor of urology of the National University of Buenos Aires, Chief of section Urology of Instituto de Rehabilitación, Government of Buenos Aires, Argentina（阿根廷国立Buenos Aires大学泌尿学教授）
Dr. Angel Ozón, Urologist of the Instituto de Rehabilitación of Buenos Aires（阿根廷国立Buenos Aires大学泌尿学医生）
Dr. Daniel Ekizian, Urologist of Instituto de Rehabilitación（阿根廷国立Buenos Aires大学泌尿学医生）
Professor Dr. med. Karl-Dietrich Sievert, Vice Chair Prof. of Urology, Director - Uro-oncology, Neurourology, Incontinence, & Reconstructive Urology Department of Urology University of Tuebingen D72076 Tuebingen, Germany（德国Tuebingen大学泌尿学教授、主任）
Holly Gilmer, MD, Chief of Pediatric Neurosurgery, Beaumont Hospital, Royal Oak, Michigan（美国Beaumont医院儿童神经外科主任）
Yegappan Lakshmanan, MD, Chief, Pediatric Urology, Children’s Hospital of Michigan（美国密西根儿童医院儿童泌尿科主任）
回复TNEGI//ETNI的评论:
Fang ZhouZi did not make up something. He did not try to set someone up. What he said about Xiao' surgery is kind of true. I would not accept someone meant to make some number does not exist. Fang never said his surgery has no effect at all. He said all those 300 hundreds people he know did not get improved at all after surgery and and the total number given by Xiao is about 2000 surgeries.
回复ingodwetrustforever的评论:
I have no reason to say something I did not read. I am sorry that I can not do what noname8888 did to get the link. I read that about 2 or 3 months ago. You can find something interesting there by yourself if you really want to know the truth.
信口开河之前，麻烦作者先读读Journal of Urology上关于的肖传国的理论和手术法的文章。
http://www.sciencedirect.com/science/article/pii/S0022534710030533
您只要稍微懂点英语，就会知道，The results is ambiguous and seriously questioned in the Journal of Urology. (引自Nature News： http://www.nature.com/news/2010/100929/full/467511a.html)
