高危人群胰腺癌筛查

Screening protocol parameters based on risk factor

Risk Factor Increased Risk Mean age at PC dx Age at which screening should begin Total years of screening
Peutz-Jehgers Syndrome 132x 40.8 30 20
Hereditary Pancreatitis 87x 54.2 45 20
p16-Leiden mutation 48x 59 50 20
Familial PC (>2 first-degree relatives with PC) 32x NA 50, or 10 years before youngest PC dx in blood relative 20
New-onset diabetes > age 50, with hx weight loss or smoking 8x 71a Time of diabetes dx 3
aSEER median age of PC diagnosis in general population

PC pancreatic cancer, hx history, dx diagnosis

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