在这些数字中,估计WHO是采用了最低的那个,是不是为了保险起见不得而知,如果是的话,那为什么对重症和住院的保护率又是100%呢?不会是所有国家的资料都是100%吧? 如果不是也应该是取最低的为准,不知道WHO是怎么弄来的这组数据,相信不会是搞错了,原话在这里:Vaccine efficacy results showed that the vaccine prevented symptomatic disease in 51% of those vaccinated and prevented severe COVID-19 and hospitalization in 100% of the studied population。
除了这个外,科兴的疫苗还不用超低温保存,很适合那些条件不是很好的第三世界国家,WHO在新闻稿中这么说:The Sinovac-CoronaVac product is an inactivated vaccine. Its easy storage requirements make it very manageable and particularly suitable for low-resource settings。中国的疫苗还有一个吸引人的地方就是比起西方的疫苗便宜,当然,WHO不好就这个做评论。
Google "covid 19 vaccine used in chile" returned this:
"A study published by researchers at the University of Chile on 6 April, in which Cortés was not involved, found that the CoronaVac vaccine was 56.5% effective in preventing infections two weeks after a second dose but only 3% effective after a single dose.Apr 20, 2021"
这个科兴疫苗在巴西的三期试验保护率是50%多点,在土耳其却达到90%,这么大的区别,是有原因的。在巴西做的8000多人,全部是一线治疗抢救新冠病人的医护,处于极端高暴露状态。也许非常可能,疫苗的保护率跟病毒浓度有关。科兴在巴西的三期,是全世界所有疫苗三期临床试验唯一完全用一线医护入组的trial。一个疫苗对高暴露的保护率与普通暴露保护率也许可以很不同。
有专家明确说,如果想比较两种不同疫苗的保护率,除非做head-to-head直接比较的临床试验,with the participating population and all other experimental conditions being kept the same。 Otherwise, comparison of the numbers is of no much use.