Melanosis coli is a condition associated with the deposition of lipofuscin (not melanin as the name might imply) in the lamina propria of the large intestines. Historically, laxatives, primarily from the anthranoid group (i.e., senna and rhubarb derivatives), are the main culprits. As these laxative supplements pass through the colon, they become active and cause cell death and apoptosis in the lining of the colon, eventually causing dark pigmentation of the colon. This activity reviews the cause of melanosis coli and highlights the role of the interprofessional team in its management.
从网上这段叙述来看,酵素或其它泻药实际上起来抑制肠息肉甚至肠癌的作用,黑点又有啥呢?