在伍迪.艾伦电影 "Play It Again, Sam" 里，艾伦采取幻想自己是棒球明星的方法，延长在床上享受性福的时间。其实现实中，性专家们更推崇一种机械的方式来治疗早泄："停止,开始,挤压(“stop, start, squeeze” )."
现在，科学家们试图使用一种新药(Dapoxetine)--与治疗抑郁症同类的药物，来解决早泄问题。
美国科学家在一项有2600人参加的试验中，发现这种新药(Dapoxetine)至少能延长性交时间3倍以上。
如果延伸试验继续支持这种效果的话，这种新药将是人类第一次专门用药物的方式研究治疗早泄问题。据称，全世界20-30%的男人都存在早泄问题。
参加试验的自愿者们一般完成性交都在1分中以内。是啊，在信鸽或赛车比赛中速度是克敌制胜法宝，但在性生活中，悠缓却是两情愉悦秘诀。
新药研制者Johnson & Johnson通过另一些自愿者研究发现，正常的性交从进入到高潮(between penetration and climax)，卡著跑表测量出来是7.3分钟。
患有抑郁症的男人，有的需要服用血液复合胺抑制剂(SSRIs)。他们有些抱怨说这种药物抑制了他们的性感觉，拖延了性高潮的到来。但对这些人是副作用的，对其他人可能就是福音。所以Johnson & Johnson 开始研究SSRI的药理来专门延缓性高潮。
今天，The Lancet发表了在美国121个研究中心所做的试验结果。试验参加者随机抽取一份试剂：可能是安慰剂，也可能是是不同剂量的新药试剂(Dapoxetine)。在性医学试验中， 安慰剂通常也是有效果的（能延长性交时间从1分钟到1.75分钟）。但新药试剂表现更好显然有明显效果：30mg能延长性交时间从1分钟到2.78分钟， 60mg延长时间从1分钟到3.32分钟。这个效果是显著的，而且只有一些参加者有副作用反应：恶心，腹泄，头疼和眩晕。
由Minnesota大学教授Jon Pryor领头的研究组认为新药试剂对"中到重症早泄病人有治疗效果，并且副作用在接受范围内。"
在这项为期12周的试验中，参加者被要求每月至少性交6次。药丸在性交前1到3小时内服下，射精及任何副作用都用记事本记录。
研究组同时认为"新药试剂改善了病人对射精的控制，提高了性交的快感。"
新药试剂尽管是SSRIs，但并不是研制来治疗抑郁症的，尽管它可能有治疗抑郁症的功能。它用1小时就在血液里达到最大浓度，并在24小时内从身体完全排除。
这种新药由Alza Corp（Johnson & Johnson 的子公司）研制，它所具有的治疗早泄奇效，可能为这家公司带来滚滚财源。如果这样的话，再体贴的女伴也没有机会继续取悦因早泄而垂头丧气的男人了, 她们假装说：
不是你射得太快，而是我来得太慢！
(注：Dapoxetine到目前为止还没有中文翻译，我翻译为维哥，借伟哥之英名。其实可音译为大炮泻停(Dapoxetine)，有泻停封的风格，呵呵)
Pill that prolongs the joy of sex
BY LEWIS SMITH
IN THE Woody Allen film Play It Again, Sam, the technique used was to think of the names of famous baseball stars, whereas some sexologists recommend the more mechanical "stop, start, squeeze" method.
Now scientists may have come up with the first pharmaceutical means of tackling premature ejaculation using a class of drug usually associated with treating depression.
In trials involving 2,600 men, researchers in the US have shown that a new drug could prolong sexual intercourse by more than three times the duration previously experienced.
If approved after more tests, the drug will be the first designed to tackle the problem, which is experienced by 20-30 per cent of men.
Participants in the trial typically concluded intercourse in less than a minute. Speed may be desirable in a racing pigeon or a sports car, but in sex the laurels tend to be won by the slow.
A "normal" time between penetration and climax, the drug manufacturers Johnson & Johnson discovered, with the aid of obliging couples and a stopwatch, is 7.3 minutes.
Men on anti-depressants called selective serotonin reuptake inhibitors ( SSRIs, the class to which Prozac and Seroxat belong ) typically complain of dulled sexual sensation and delayed orgasm. But what is a curse for them may be a benefit for others, so Johnson & Johnson set out to develop an SSRI specifically for delaying orgasms.
Today The Lancet publishes the results of trials carried out at 121 centres in the United States. Men were randomly given either placebos or different doses of dapoxetine. As is typical in sexual studies, the placebo proved pretty effective, prolonging intercourse from less than one minute to 1.75 minutes. But the drug did better. A 30mg dose produced 2.78 minutes and
a 60mg dose 3.32 minutes. While hardly Don Juan standard, this was a significent result, marred only by some side-effects. Nausea, diarrhoea, headache and dizziness were reported.
Nevertheless, the team, led by Professor Jon Pryor, of the University of Minnesota, concluded that dapoxetine was "an effective and generally well- tolerated treatment for men with moderate-to-severe premature ejaculation".
During the trial, which lasted twelve weeks, couples were asked to attempt intercourse six times or more per month. The tablets were to be taken between one and three hours before starting intercourse, and the time to ejaculation and any side-effects were to be noted in a logbook.
"Dapoxetine also improved patientsó perception of control over ejaculation, satisfaction with sexual intercourse and overall impression of change in condition," the team noted. "Partners benefited through improved satisfaction with sexual intercourse."
Dapoxetine, although an SSRI, is not designed to ease depression, though that may be a useful side-effect in some cases. It takes only an hour to achieve maximum concentration in the blood and is virtually eliminated from the body within 24 hours.
Dapoxetine is made by Alza Corp, of Mountain View, California, a wholly owned subsidiary of Johnson & Johnson. Given the prevalence of premature ejaculation, it could become a money-spinner. If so, it will eliminate an opportunity for perfect sexual manners of the kind exhibited by caring women. "It's not that you're too fast, but that I'm too slow," may be a lie, but
it has consoled many a despairing man.
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