氨基葡萄糖使用者注意
Glucosamine 受到不少关节炎、痛的患者使用，但目前医学上并未能证实它对关节内软骨有修复作用和对关节炎、痛有治疗作用。不幸的是，它会恶化人体对胰岛素抵制作用，增加血糖而加重糖尿病。
MSM 也尚未证实其医学价值，有研究报告建议使用不应超过 12 周，其付作用有胃痛，腹泻和头痛，长期使用的安全性有待进一步研究。
个体对使用以上两种“药物” 反映不同，但临床研究两组人群发现：用“药” 组与用“安慰剂 (placebo) ” 组无区别。
有网友问及其他许多关节营养品，例如 hydrolyzed gelatin (NutraJoint), Cetyl Myrist, Flax seed oil--fish oil, Chondroitin sulphate and GLA, 釆用这些补充品的原理基于它们是人类骨质、胶原蛋白的成分，但服用这类物质有无真正的作用？目前仍无证据显示。长期服用的付作用也正在研究之中。 2008 年在家庭医师专业刊物上有研究报告，服用 fish oil, omega-3 sources 并无医学临床效果(无作用)。
Glucosamine supplements: Can they rebuild cartilage?
Answer
Many manufacturers market dietary supplements that they claim can rebuild cartilage. But little scientific evidence supports this claim. The most studied of these supplements is glucosamine sulfate.
Glucosamine is a natural compound in your body that helps make your cartilage strong and rigid. Glucosamine is also sold as a nutritional supplement in many drugstores and health food stores.
Osteoarthritis causes the breakdown of joint cartilage and can affect any joint. Because glucosamine is a component of normal cartilage, it is thought that glucosamine supplements may be able to help the body repair damaged cartilage. But this has not been proved.
If you have arthritis, consult with your doctor before you start taking glucosamine supplements.
Glucosamine: Does it affect blood sugar?
Answer
Some preliminary studies suggest that glucosamine may worsen insulin resistance, which contributes to elevated blood sugar levels in people with type 2 diabetes. Although more research is needed to clarify these findings, it's probably a good idea to avoid taking glucosamine if you have type 2 diabetes.
It's important to note that glucosamine hasn't been proven to improve joint pain associated with osteoarthritis. So, if osteoarthritis pain is a problem, consult your doctor about treatment options.
MSM for arthritis pain: Is it safe?
Answer
Few studies have examined the long-term effects of the dietary supplement called methylsulfonylmethane (MSM). One study suggested that it's safe to take MSM for up to 12 weeks. But further research is needed to assess its safety for long-term use.
There's no conclusive evidence that MSM is effective in reducing arthritis pain. Two small studies have suggested that MSM may reduce joint pain in people with osteoarthritis. Side effects of MSM may include stomach upset, diarrhea and headache.
Although there is great interest in using MSM to treat a variety of conditions, including arthritis, more research is needed to determine its potential benefits and risks.
More information about the supplements
Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis.
GLA, or gamma linolenic acid . the right balance of omega-3s as well as GLA from the omega-6 family, much like it needs the proper combination of vitamins and minerals for smooth-running metabolic functions. So if you've been primarily focusing on the omega-3 sources of good fats.
