治疗糖尿病的 胰岛素 方面的研究和成果 起始与1920年代。
50年代后期和60年代前期 人工成功合成完整有生物活性的 牛胰岛素(能治疗人的糖尿病。此前 是利用猪 牛的 胰腺的 直接的 胰岛素提取纯化 小批量生成),中国科学家 经过艰难的钻研和实验 最先取得这一划时代的成果。化学 和 生物化学技术。
1976年 美国lilly 药厂 率先实行了 利用 细菌复制 胰岛素的 甲/A 或 乙/B 链,再 生化组合成 AB/甲乙 2链完整的 全 人胰岛素,开创了大批量生成 人用胰岛素。 DNA recombination 技术。
http://www.sciencemag.org/content/153/3733/281.extract
Science 15 July 1966:
Vol. 153 no. 3733 pp. 281-283
DOI: 10.1126/science.153.3733.281
Total Synthesis of Insulin in Red China - Science
www.sciencemag.org › 15 July 1966
Science
by VK Mcelheny - 1966 - Cited by 3 - Related articles
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